Kappa Light Chain [L1C1]

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This antibody recognizes kappa light chains of human immunoglobulins, which may be useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin’s lymphomas (1-5). The most common feature of these malignancies is the restricted expression of a single light chain class.

Category: Primary Antibodies

Description

Description

The normal human kappa/lambda ratio is approximately 2:1. The presence of clear cut light chain restriction with a kappa/lambda ratio more than 10:1 is consistent with a malignant proliferation (2,6). Specifications

INTENDED USE	RUO
FORMAT	Concentrate, Predilute, VALENT
VOLUME	0.1 ml, 1.0 ml, 20 ml, 6.0 ml
SOURCE	Mouse Monoclonal
CLONE	L1C1
ISOTYPE	IgG1
ANTIGEN	Kappa immunoglobulin light chain
LOCALIZATION	Cytoplasmic
POSITIVE CONTROL	Tonsil or bone marrow