Description
The Cytokeratin 18 antibody (CK18) [DC10] is a 45 kDa acidic intermediate filament protein. It is typically co-expressed with Cytokeratin 8 and is present in the majority of simple ductal and glandular epithelia. Research indicates that this antibody interacts with numerous simple epithelia, including those of the gastrointestinal tract, lung, breast, pancreatic, ovary, and thyroid cancers, whereas it does not respond with tumor cells of non-epithelial origin, such as glioma, melanoma, and osteosarcoma. It also does not interact with stratified squamous epithelium in most cases of squamous cell cancer.
Specifications
| Weight | N/A |
|---|---|
| Dimensions | N/A |
| Intended Use | RUO |
| Species Reactivity | Human |
| Source | Mouse Monoclonal |
| Clone | DC10 |
| Isotype | Mouse IgG1 |
| Antigen | Cytokeratin 18 |
| Localization | Cytoplasmic |
| Positive Control | Colon, Skin |
