Description
A 40 kDa polypeptide reacts with a type I keratin known as cytokeratin 17 antibody (CK17). Hair follicles and other human epithelial appendages are affected by CK17 staining. According to studies, CK17 may be a very good marker for squamous cell carcinomas in a variety of tissues, such as the oral cavity, lung, and cervix. Additionally, CK17 might be useful in differentiating myoepithelial cells from the luminal epithelium of several glands, including the breast, sweat, and salivary glands. High tumor grade, positive axillary lymph nodes, and a poorer prognosis have all been linked to positive CK17 expression in breast cancer.
