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Description

One important apoptosis regulator that can either encourage or prevent cell death is BCL-2. Dimerizing to further regulate apoptosis is another characteristic of the BCL-2 family. For instance, it has been discovered that Bag1 and BCL-2 form a heterodimer, which strengthens BCL-2’s anti-apoptotic action. It has been demonstrated that Bakand Bax are essential for the release of cytochrome from mitochondria, which startsapoptosis. Bax affects cells in a way that promotes apoptosis rather than inhibits 

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