Description
TRPS1 (Trichorhinophalangeal Syndrome 1) is a gene that encodes a transcription factor involved in the development of several organs and tissues. This gene plays an essential role in regulating the growth and differentiation of cells, particularly in the hair follicles, bones, and skin. Mutations in the TRPS1 gene are associated with Trichorhinophalangeal Syndrome type 1 (TRPS1), a genetic disorder that affects hair, facial features, and the development of bones and nails. The syndrome is characterized by sparse or absent hair, distinctive facial features, and skeletal abnormalities. TRPS1 is a DNA-binding rotein with specific involvement in regulating genes that control the growth and differentiation of epithelial and mesenchymal cells, making it essential for normal development. In addition to its role in genetic disorders, TRPS1 also has implications in cancer biology, particularly in understanding certain epithelial and esenchymal cell-related tumors.
