CA19-9

121SLE/Mouse/Monoclonal

Gene Bio Solution CA19-9 Antibody. Gene bio solution’s mouse recombinant antibody recognizes CA19-9, a carbohydrate epitope expressed on a high MW (>400kDa) mucin glycoprotein. CA19-9 is a sialyl Lewis a structure which is synthesized from type 1 blood group precursor chains and is present in individuals expressing the Lewis a and/or Lewis b blood group antigens. In normal tissues, CA19-9 or sialyl Lewis a antigen is present in ductal epithelium of the breast, kidney, salivary gland, and sweat glands. CA19-9’s expression is greatly enhanced in serum as well as in the majority of tumor cells in gastrointestinal (GI) carcinomas, including adenocarcinomas of the stomach, intestine, and pancreas. Preoperative elevated CA19-9 levels in patients with stage I pancreatic carcinoma decrease to normal CA19-9 values following surgery. When used serially, CA19-9 can predict recurrence of disease prior to radiographic or clinical findings.

Gene bio solution is a leader in recombinant monoclonal IVD antibodies for immunohistochemistry (IHC) offering 400+ tumor and tissue specific relevant products developed by a pathologist for pathologists. Visit Precision Recombinant Antibodies – IVD Antibodies – About Gene bio solution (genebiosolution.com) to learn more about Gene bio solution.

Specifications

Species Reactivity

Humans; others not tested

Known Applications

Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)

Supplied As

Buffer with protein carrier and preservative

Storage

Store at 2ºC to 8ºC

Control

Colon carcinoma

Visualization

Cytoplasmic

Isotype

IgM

Immunogen

Precipitin lines obtained after immuno-diffusion using MAb 116-NS-19-9 and mucins isolated from an ovarian cyst of a Lewis A+B-patient (0Le)

Ordering Information

Format:

Volume:

  • Classification
  • RUO
  • Catalogue Number
  • GBS2072RP

Format:

Volume:

  • Classification
  • RUO (EU)
  • Catalogue Number
  • GBS2072RP