C4d

ZM78/Mouse/Monoclonal

Gene Bio Solution C4d Antibody. Gene bio solution’s mouse recombinant antibody recognizes C4d, a stable split product remnant of classical complement activation, which becomes covalently bound to endothelium and basement membrane, after induction of the classical antibody-induced pathway. As an established marker of antibody-mediated acute renal allograft rejection and its proclivity for endothelium, C4d component can be detected in peritubular capillaries in both chronic renal allograft rejection as well as hyperacute rejection, acute vascular rejection, acute cellular rejection, and borderline rejection. C4d has been shown to be a significant predictor of transplant kidney graft survival and is an aid in treating acute rejection.

Gene bio solution is a leader in recombinant monoclonal IVD antibodies for immunohistochemistry (IHC) offering 400+ tumor and tissue specific relevant products developed by a pathologist for pathologists. Visit Precision Recombinant Antibodies – IVD Antibodies – About Gene bio solution (genebiosolution.com) to learn more about Gene bio solution.

Specifications

Species Reactivity

Humans; others not tested

Known Applications

Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)

Supplied As

Buffer with protein carrier and preservative

Storage

Store at 2ºC to 8ºC

Control

Acute rejected kidney transplant

Visualization

Membrane or cytoplasmic

Isotype

IgG1 /κ

Immunogen

Recombinant full-length human complement 4d protein

Ordering Information

Format:

Volume:

  • Classification
  • RUO
  • Catalogue Number
  • GBS2388RP

Format:

Volume:

  • Classification
  • RUO (EU)
  • Catalogue Number
  • GBS2388RP