Description
Anti-Human Immunoglobulins (IgA, IgG, IgM) Polyvalent
Anti-human immunoglobulins (IgA, IgG, IgM) polyvalents are antibodies that target and bind to different classes of human immunoglobulins. These antibodies are valuable tools in various laboratory applications, including immunohistochemistry, immunoblotting, and flow cytometry. They enable the detection and quantification of specific immunoglobulins in biological samples.
IgA Antibodies: Immunoglobulin A (IgA) is a crucial antibody found in mucosal secretions, such as saliva, tears, and mucous membranes. IgA plays a vital role in mucosal immunity by neutralizing pathogens and toxins before they can enter the bloodstream. Anti-IgA polyvalent antibodies bind specifically to IgA molecules, facilitating their detection and analysis in biological samples.
IgG Antibodies: Immunoglobulin G (IgG) is the most abundant antibody in the bloodstream and plays a central role in the adaptive immune response. IgG antibodies recognize and bind to pathogens, marking them for destruction by other immune cells. Anti-IgG polyvalent antibodies target IgG molecules, allowing for the precise detection and measurement of IgG levels in various biological samples.
IgM Antibodies: Immunoglobulin M (IgM) is the first antibody produced during an initial immune response to an infection. It is primarily found in the bloodstream and is effective at neutralizing pathogens in their early stages of invasion. Anti-IgM polyvalent antibodies specifically bind to IgM molecules, enabling researchers to assess IgM levels in serum or plasma samples.
Applications:
- Immunohistochemistry: Anti-human immunoglobulin polyvalent antibodies are used to localize and visualize specific immunoglobulins within tissues, aiding in the diagnosis of various diseases.
- Immunoblotting: These antibodies are employed to detect and quantify immunoglobulins in protein samples separated by gel electrophoresis.
- Flow Cytometry: Anti-Ig antibodies facilitate the identification and analysis of different immune cell populations based on their surface immunoglobulin expression patterns.
