Description
The CD103 antibody identifies the integrin subunit CD103 cell surface antigen, which is typically expressed in hairy cell leukemia (HCL), a B-cell lymphoproliferative illness CD103 [EP206] exhibits reactivity in FFPE (formalin-fixed paraffin-embedded) tissue, obviating the necessity for flow cytometric analysis or frozen section IHC, so serving as a significant enhancement to an immunohistochemistry (IHC) panel for the diagnosis of HCL. Additional antibodies utilized alongside CD103 for the identification of HCL comprise CD25, TIA-1, DBA44, and CD11c. Intraepithelial CD8 (+) tumor-infiltrating lymphocytes (TIL) expressing CD103 are significantly correlated with patient survival in high-grade serous ovarian cancer (HGSC).
Specifications
| Intended Use | RUO |
|---|---|
| Format | Concentrate, Predilute |
| Volume | 0.1 ml, 0.5 ml, 6.0 ml |
| Source | Rabbit Monoclonal |
| Clone | EP206 |
| Isotype | IgG |
| Antigen | A synthetic peptide corresponding to the residues of human CD103 protein |
| Localization | Cell Membrane |
| Positive Control | Hairy cell leukemia |
