Description
Apo lipoprotein J, another name for clusterin antibodies, has been linked to a number of activities, including active cell death. Anaplastic large cell lymphoma (ALCL), as well as pancreatic, breast, prostate, and ovarian malignancies, have been shown to overexpress clusterin, which is expressed in the normal brain. 95% of systemic ALCL, including 100% of ALK-1(+) and 91% of ALK-1(-) ALCL, can be stained by clusterin. Clusterin may be a helpful diagnostic marker for ALCL, particularly in cases of ALK-1(-), according to studies. For patients with ovarian cancers, clusterin overexpression seems to be a helpful prognostic factor.
Specifications
| Weight | N/A |
|---|---|
| Dimensions | N/A |
| Intended Use | RUO |
| Species Reactivity | Human |
| Source | Mouse Monoclonal |
| Clone | 41D |
| Isotype | IgG1/kappa |
| Antigen | Clusterin alpha chain |
| Localization | Cytoplasmic or paranuclear |
| Positive Control | Brain or anaplastic large cell lymphoma |
