Description
The 66 kDa protein known as the estrogen receptor antibody (ER) functions as a nuclear hormone receptor that is dependent on estrogen. The nuclei of epithelial cells in normal breast and endometrial tissues, as well as a fraction of breast carcinomas, have been found to contain ER, according to studies. The six functionally distinct domains of the ER protein are designated A through F. The amino-terminal domain in the A/B region of ER-alpha is reacted with by ER [1D5]. Numerous studies on breast cancer have published this clone, which has been shown to function in tissues that have been paraffin-embedded and treated with formalin.