Lambda Light Chain [N10/2]

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This antibody recognizes lambda light chains of human immunoglobulins, which may be useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin’s lymphomas (1-5). The most common feature of these malignancies is the restricted expression of a single light chain class.

Category: Primary Antibodies

Description

Description

The normal human kappa/lambda ratio is approximately 2:1. The presence of clear cut light chain restriction with a kappa/lambda ratio more than 10:1 is consistent with a malignant proliferation (2,6). Specifications

INTENDED USE	RUO
FORMAT	Concentrate, Predilute, VALENT
VOLUME	0.1 ml, 1.0 ml, 20 ml, 6.0 ml
SOURCE	Mouse Monoclonal
CLONE	N10/2
ISOTYPE	IgG1
ANTIGEN	Lambda immunoglobulin light chain
LOCALIZATION	Cytoplasmic
POSITIVE CONTROL	Tonsil or bone marrow