Description
Studies have shown accurate categorization of ductal vs. lobular neoplasia in the breast with a cocktail of p120 + E-cadherin and helped give further clarification in the separation of low-grade ductal carcinoma in situ from lobular neoplasia. Of other tumors that may morphologically mimic lobular carcinoma, diffusely infiltrating variants of rectal and gastric carcinomas have shown diffuse cytoplasmic p120 immunostaining (1-2). In conclusion, this Multiplex IHC stain may enable the identification of the presence and the extent of the lobular lesions due to its bright pink color in lobular lesions, and therefore may aid in providing a more accurate diagnosis.
Specifications
| WEIGHT | N/A |
|---|---|
| DIMENSIONS | N/A |
| INTENDED USE | RUO |
| SPECIES REACTIVITY | Human |
| SOURCE | Mouse Monoclonal, Rabbit Monoclonal |
| CLONE | 98/pp120, EP6 |
| ISOTYPE | IgG1, IgG |
| ANTIGEN | anti-p120, anti-E-cadherin |
| LOCALIZATION | Cytoplasmic, Membrane |
| POSITIVE CONTROL | Breast cancer |
