Description
There is an excellent correlation between CD20 and Pax-5 expression; however, anti-Pax-5 exceeds the specificity and sensitivity of L26 (CD20) because of its earlier expression in B-cell differentiation and its ability to detect all committed B-cells, including classic Hodgkin’s lymphoma. It is very specific to B-cell lineage and does not stain T-cells. In essence, PAX-5 may be a superior pan B-cell marker to CD20 (see reference).
Specifications
| INTENDED USE | RUO |
|---|---|
| SPECIES REACTIVITY | Human |
| SOURCE | Mouse Monoclonal |
| CLONE | BC/24 |
| ISOTYPE | IgG1 |
| ANTIGEN | PAX-5 (B-cell) |
| LOCALIZATION | Nuclear |
| POSITIVE CONTROL | Tonsil |
