Description
Uroplakin II is a 15 kDa protein constituent of urothelial plaques. Research indicates that
Uroplakin II mRNA has great specificity and is expressed in both bladder cancer tissues
and the peripheral blood of individuals with primary and metastatic urothelial carcinoma
of the bladder. The Uroplakin II antibody [BC21] demonstrated enhanced sensitivity
(46/59, 78%) relative to Uroplakin III [AU1] (191/56, 34%) in instances of urothelial
carcinoma of the bladder, excluding the bladder and ureter; staining exhibited high
specificity across diverse normal and neoplastic tissues in an internal study. Uroplakin II
antibody [BC21] is a highly specific antibody potentially valuable for the identification of
malignancies originating from urothelium.
